Hypoglycaemia in Type 2 diabetes

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Hypoglycaemia in Type 2 diabetes

The primary cause of hypoglycaemia in Type 2 diabetes is diabetes medication-in particular, those which raise insulin levels independently of blood glucose, such as sulphonylureas (SUs) and exogenous insulin. The risk of hypoglycaemia is increased in older patients, those with longer diabetes duration, lesser insulin reserve and perhaps in the drive for strict glycaemic control. Differing defin...

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Pharmacogenomic approach in type 2 diabetes treatment

Introduction: Type 2 diabetes (T2D) is chronic health caused by the interaction between genetic and environmental factors that results in high blood glucose. The evidence-based guidelines for diabetes management are mainly based on lifestyle changes, control of risk factors, and the management of blood glucose levels. Although numerous antidiabetic agents have been developed over time, T2D trea...

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Hypoglycaemia, chronic kidney disease and death in type 2 diabetes: the Hong Kong diabetes registry

BACKGROUND In patients with type 2 diabetes, chronic kidney disease (CKD) is associated with increased risk of hypoglycaemia and death. Yet, it remains uncertain whether hypoglycaemia-associated mortality is modified by CKD. METHODS Type 2 diabetic patients, with or without CKD at enrolment were observed between 1995 and 2007, and followed up till 2009 at hospital medical clinics. We used add...

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Recurrent hypoglycaemia in a patient with type 1 diabetes.

To cite: Tan HL, Manjunatha R, Barton D. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2014-205613 DESCRIPTION A 31-year-old woman with a 20-year history of type 1 diabetes presented with a 2-month history of recurrent disabling hypoglycaemia. Common causes of hypoglycaemia which included excess insulin, missing meals and unaccustomed exercise had been excluded...

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Pubertal stage and hypoglycaemia counterregulation in type 1 diabetes.

AIMS To compare physiological and autonomic responses to acute hypoglycaemia in diabetic children in pre-, mid-, and post-pubertal stages of development. METHODS Twenty seven children (8 pre-pubertal, 7 mid-pubertal, 12 post-pubertal) with type 1 diabetes were studied. Hypoglycaemia was induced by insulin infusion until an autonomic reaction (R) was identified. Counterregulatory hormone level...

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ژورنال

عنوان ژورنال: Diabetes Research and Clinical Practice

سال: 2008

ISSN: 0168-8227

DOI: 10.1016/j.diabres.2008.09.026